Recent data do not support that nitrofurantoin and alcohol causes a disulfiram-like reaction or other adverse reactions/toxicities. Historical studies have suggested that alcohol use with nitrofurantoin resulted in a disulfiram-like reaction (40,–42). Likewise, a study found that alcohol did not cause a disulfiram-like reaction with nitrofurantoin in volunteers (44). Alcohol may adversely affect the PK […]
